Mogroside V: Why is a high-purity extract (>98%) the key to efficacy?

In the arena of natural sweeteners,  is rewriting industry rules with its superior performance, and its high-purity extract of over 98% has become the gold standard for its outstanding efficacy.

01 The essence of Mogroside V

Mogroside V is the core active ingredient in monk fruit, belonging to the triterpenoid saponin class of compounds.

The sweetness of mogroside V originates from its specific binding to sweet taste receptors, and its taste duration is 2-3 times longer than that of sucrose. This sustained sweetness makes it an ideal substitute for sucrose in the food and beverage industry.

02 Purity determines efficacy: The core value of >98% high-purity extracts

The content of Mogroside V extract typically ranges from 20% to 80%, while extracts with a purity of >98% represent the industry's top level. Why high purity?

1. A qualitative change in the sweetness experience

Low-purity extracts (such as 30%-50%) often contain other saponin components, such as mogroside IV, which is only 126 times sweeter than sucrose and has a distinct bitter aftertaste and a licorice-like aftertaste.

High-purity Mogroside V (>98%) exhibits a pure, sugar-like sweetness with almost no unpleasant aftertaste, greatly enhancing the sensory quality of the product.

2. Precise control of physiological activity

Studies have shown that：Mogroside V has various physiological activities, including lowering blood sugar, anti-oxidation, and liver protection.

Antioxidant:： High-purity sucralose V can scavenge 50%-60% of DPPH free radicals.

Anti-inflammatory: In in vitro models, it inhibits the release of inflammatory factors (such as IL-1β) by 30%-40%.

Hydroxyglycemic effect: With a glycemic index ≤10, it is suitable for use by diabetic patients.

When the purity reaches >98%, we can more precisely control the functionality and consistency of the product, providing reliable raw materials for the development of pharmaceuticals and high-end health products.

3. Stability of mogrosides

High-purity Mogroside V exhibits good stability in a dry state—its content decreases by ≤5% after 12 months of storage at 25°C.

Impurities in low-purity products can become destabilizing factors, especially in aqueous solutions, where degradation is accelerated at temperatures above 60°C.

03 Application scenarios: The differentiated advantages of high-purity Mogroside V

The applications of mogrosides of different purities vary significantly.：

The irreplaceable nature of high-purity Mogroside V

1,Pharmaceutical field：

Studies have shown that high-purity Mogroside V with a purity of >98% has a preventive and therapeutic effect on CCl4-induced chronic liver injury in rats and exhibits a certain anti-liver fibrosis effect.

2,Clinical trials：

Raw materials with clearly defined components and precise content are required to ensure the reproducibility and scientific validity of experimental results.

3,High-end functional foods：

Weight management products for obese individuals – research shows that mogrosides can reduce weight by 11.9% and body fat by 35.7% in rats.

04 Identifying genuine high-purity mogrosides

Key performance indicators

1,Testing methods and standards：

HPLC test reports are currently the most accurate quantitative analysis method. It's also important to check whether the report complies with group standards such as T/CI 967-2025.

2,physical properties：

High-purity mogrosides are usually white powder, and the lower the purity, the darker the color (yellow to brownish-yellow).

3,Solubility and taste：

It is readily soluble in water and ethanol, and has a pure sweet taste with no aftertaste of bitterness.

4,Supplier Qualification：

Choose companies with Good Manufacturing Practice (GMP) certification for plant extracts to ensure that the production process complies with standards such as T/CCCMHPIE 1.106-2025.

Driven by the upgrading of health consumption, the market's demand for natural sweeteners has gone beyond simple "sweetness replacement" and is shifting towards high-end products with precise efficacy and excellent quality.

With its superior sweetness and definite physiological activity, >98% high-purity mogrosides are becoming the "gold standard" in pharmaceutical, health product, and high-end food formulations, representing the future development direction of the plant extract industry.